State police responded to the crash around 11 p.m. Monday near the 218-mile marker of southbound I-65.

At least one person is dead after multiple semis crashed and caught on fire on Interstate 65 in Jasper County Monday night.

Lane closures will continue to affect drivers in downtown Louisville this weekend as road work on Interstate 65 continues.

Police believe Daryus Chambers, 37, crashed into a tractor-trailer and then was run over by another motorcyclist.

A single-vehicle crash on Interstate 65 has led to a complete road closure near mile marker 306. The incident occurred at ...

Southbound I-65 in southeast Indianapolis will close this weekend as crews continue progress on drainage improvements beneath the interstate. Southbound I-65 is scheduled to close at 9 p.m. on Friday ...

A new contract will allow for work on I-65’s “Hospital Curve.” Work will require a temporary interstate closure the weekend ...

NASHVILLE, Tenn. (WSMV) - A motorcyclist was killed on Friday night on Interstate 65 North just behind the Briley Parkway ...

Starting at 8 p.m. Friday and continuing through 5 a.m. Monday, July 28, crews will close the left three lanes of the Kennedy ...

Indiana drivers will need to be aware of a closure this weekend on Interstate 65.Crews will temporarily close the eastbound ...

Man dies in motorcycle collision on Interstate 65 in Nashville; another rider injured, tractor-trailer involved.